What are the side effects of Kayexalate
Andrew Campbell
Published Apr 08, 2026
loss of appetite,upset stomach,nausea,vomiting,constipation, or.diarrhea.
What should I monitor after giving KAYEXALATE?
Monitor serum potassium during therapy because severe hypokalemia may occur. KAYEXALATE is not totally selective for potassium, and small amounts of other cations such as magnesium and calcium can also be lost during treatment. Monitor calcium and magnesium in patients receiving KAYEXALATE.
When should you not give KAYEXALATE?
KAYEXALATE is contraindicated in the following conditions: patients with hypokalemia, patients with a history of hypersensitivity to polystyrene sulfonate resins, obstructive bowel disease, neonates with reduced gut motility (postoperatively or drug induced) and oral administration in neonates (see PRECAUTIONS).
What are the side effects of sodium polystyrene?
- constipation.
- seizures.
- unusual bleeding.
- confusion.
- muscle weakness.
- abdominal pain.
- fast, pounding, or irregular heartbeat.
How long does it take for KAYEXALATE to take effect?
Many of us were taught that if you give a patient a dose of kayexalate, you should expect there serum potassium to drop by 0.5 – 1.0 mEq in 4-6 hours.
What is Kayexalate used to treat?
This medication is used to treat a high level of potassium in your blood. Too much potassium in your blood can sometimes cause heart rhythm problems. Sodium polystyrene sulfonate works by helping your body get rid of extra potassium.
Does Kayexalate induce diarrhea?
KAYEXALATE may cause some degree of gastric irritation. Anorexia, nausea, vomiting, and constipation may occur especially if high doses are given. Also, hypokalemia, hypocalcemia, and significant sodium retention, and their related clinical manifestations, may occur (see WARNINGS). Occasionally diarrhea develops.
What does calcium gluconate do to the heart?
Rapid intravenous injections of calcium gluconate may cause hypercalcaemia, which can result in vasodilation, cardiac arrhythmias, decreased blood pressure, and bradycardia. Extravasation of calcium gluconate can lead to cellulitis.Does Kayexalate cause edema?
Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: muscle weakness/spasms, fast/irregular heartbeat, mental/mood changes (such as irritability, confusion, slowed thinking), swelling hands/ankles/feet.
How can I lower my potassium level?- Reduce your potassium intake. One of the easiest ways to lower your potassium levels naturally is to reduce the amount of potassium in your diet. …
- Check your salt substitutes. Some salt substitutes are also high in potassium. …
- Drink more water. …
- Avoid certain herbs.
Why is Kayexalate used in renal patients?
Sodium polystyrene sulfonate (SPS) (Kayexalate®) is a cation exchange resin that trades sodium ions for potassium ions, mostly in the large intestine, to enhance the fecal elimination of excess potassium.
At what potassium level should Kayexalate be given?
They concluded that a 30-g dose of SPS should be administered to patients with serum potassium levels of between 5 and 6 mEq/L, and that a 60-g dose should be given to those with serum potassium levels of greater than 6.0 mEq/L.
What is the side effects of metoclopramide?
- feeling restless;
- feeling drowsy or tired;
- lack of energy;
- nausea, vomiting;
- headache, confusion; or.
- sleep problems (insomnia).
Is Kayexalate safe?
Safety Announcement [ 09-06-2017 ] The U.S. Food and Drug Administration (FDA) is recommending that patients avoid taking the potassium-lowering drug sodium polystyrene sulfonate (Kayexalate) at the same time as any other medicines taken by mouth.
What are the symptoms of high potassium levels?
- Abdominal (belly) pain and diarrhea.
- Chest pain.
- Heart palpitations or arrhythmia (irregular, fast or fluttering heartbeat).
- Muscle weakness or numbness in limbs.
- Nausea and vomiting.
Which medical condition is treated by intravenous administration of calcium gluconate?
Calcium gluconate is the calcium salt of gluconic acid, an intravenous medication used to treat conditions arising from calcium deficiencies such as hypocalcemic tetany, hypocalcemia related to hypoparathyrodism, and hypocalcemia due to rapid growth or pregnancy.
Should Kayexalate be taken with food?
KAYEXALATE powder is usually given by mouth mixed in a small amount of water. It can also be mixed with food or sweetened liquid Do NOT mix KEYEXALATE with orange juice or fruit juice which contains potassium.
What are the side effects of mannitol?
- dry mouth.
- excessive thirst.
- headache.
- nausea.
- vomiting.
- excess urination.
Why is Kayexalate given with sorbitol?
Background: Kayexalate (sodium polystyrene sulphonate) in sorbitol is commonly used to treat hyperkalemia in patients with renal insufficiency. Isolated case reports and one recent large series have documented intestinal necrosis following administration of kayexalate in sorbitol.
What happens if potassium is too high?
Having too much potassium in your blood can be dangerous. Potassium affects the way your heart’s muscles work. When you have too much potassium, your heart may beat irregularly, which in the worst cases, can cause heart attack. If you think you are having a heart attack, call 911 for emergency help.
How much water do I mix with Kayexalate?
One level teaspoon contains approximately 3.5 g of KAYEXALATE and 15 mEq of sodium. Suspend each dose in a small quantity of water or syrup, approximately 3 to 4 mL of liquid per gram of resin. Administer with patient in an upright position [see Warnings and Precautions (5.4)].
What are the side effects of haloperidol?
- dry mouth.
- increased saliva.
- blurred vision.
- loss of appetite.
- constipation.
- diarrhea.
- heartburn.
- nausea.
What are the side effects of neostigmine?
- excessive saliva production.
- excessive sweating.
- nausea.
- vomiting.
- diarrhea.
- stomach cramps.
What are the side effects of oxybutynin?
Oxybutynin may cause anxiety, confusion, irritability, sleepiness or unusual drowsiness, or hallucinations (seeing, hearing, or feeling things that are not there). These symptoms are more likely to occur when you begin taking this medicine, or when the dose is increased.
What are the contraindications of calcium gluconate?
- sarcoidosis.
- a high amount of calcium in urine.
- high amount of calcium in the blood.
- ventricular fibrillation, a heart rhythm disorder.
- kidney stones.
- decreased kidney function.
- poisoning by the heart medication digitalis.
- chronic kidney disease stage 3B (moderate)
Is it safe to take calcium gluconate?
Do not take calcium gluconate or antacids that contain calcium without first asking your doctor if you also take other medicines. Calcium can make it harder for your body to absorb certain medicines. Calcium gluconate works best if you take it with food. Follow all directions on your medicine label and package.
Does calcium gluconate increase blood sugar?
Calcium given before IV glucose tolerance test and IV or oral calcium by itself did not alter blood glucose and plasma IRI concentrations in either group.
Can drinking a lot of water lower potassium?
Excessive water consumption may lead to depletion of potassium, which is an essential nutrient. This may cause symptoms like leg pain, irritation, chest pain, et al. 6. It may also cause too much urination; when you drink lots of water at once, you tend to urinate frequently.
Are eggs high in potassium?
One large egg contains about 63 mg of potassium. 1 Eggs are considered a low-potassium food, but check with your doctor or dietitian to find out how often you should eat them.
Which drugs cause high potassium?
- ARBs (angiotensin II receptor blockers). …
- ACE (angiotensin converting enzyme) inhibitors. …
- Spironolactone. …
- NSAIDs (non-steroidal anti-inflammatory drugs). …
- Cyclosporine and tacrolimus. …
- Heparin. …
- Propranolol and labetalol.
What is the emergency treatment for hyperkalemia?
Membrane stabilization by calcium salts and potassium-shifting agents, such as insulin and salbutamol, is the cornerstone in the acute management of hyperkalemia. However, only dialysis, potassium-binding agents, and loop diuretics remove potassium from the body.